Researchers linked low levels of vitamin D in childhood with increased risk of subclinical atherosclerosis 25 years later in adulthood, scientists from Finland claim.
Atherosclerosis has been linked with cardiovascular risk factors, predicting cardiovascular events.
“Our results showed an association between low vitamin D levels in childhood and increased occurrence of subclinical atherosclerosis in adulthood,” said author Markus Juonala from University of Turku, Finland. “The association was independent of conventional cardiovascular risk factors including serum lipids, blood pressure, smoking, diet, physical activity, obesity indices and socioeconomic status,” Juonala added.
In the study, researchers examined the correlation between low vitamin D during childhood and increased carotid initm-thickness (IMT) in adults, a marker for structural atherosclerosis. Scientists analyzed 2,148 participants aged between 3 and 18 years as baseline, and re-examined at ages ranging between 30 and 45.
The results showed that low levels of vitamin D during childhood had a significantly higher dominance in high-risk IMT as adults.
The findings were published in the Journal of Clinical Endocrinology and Metabolism.